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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC42EP4
All Species:
15.45
Human Site:
S141
Identified Species:
37.78
UniProt:
Q9H3Q1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3Q1
NP_036253.2
356
37980
S141
K
L
P
K
S
L
S
S
S
P
V
K
K
A
N
Chimpanzee
Pan troglodytes
XP_511657
356
37938
S141
K
L
P
K
S
L
S
S
S
P
V
K
K
A
N
Rhesus Macaque
Macaca mulatta
XP_001087677
356
38026
S141
K
L
P
K
S
L
S
S
S
P
V
K
K
A
N
Dog
Lupus familis
XP_533114
352
37250
S141
K
L
P
K
S
L
S
S
S
P
V
K
K
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM96
349
37851
P141
P
K
S
L
S
S
S
P
V
K
K
A
D
A
R
Rat
Rattus norvegicus
A1A5P0
388
41010
S152
A
S
S
T
D
G
R
S
G
Y
G
L
E
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521534
374
39662
V141
K
S
L
S
S
S
P
V
K
R
V
A
E
E
E
Chicken
Gallus gallus
XP_001233620
302
32279
R100
R
D
M
L
G
S
L
R
D
S
A
L
F
V
K
Frog
Xenopus laevis
NP_001084868
300
33097
S97
D
R
R
D
M
L
G
S
L
R
D
S
A
I
F
Zebra Danio
Brachydanio rerio
XP_001336703
336
36758
S134
T
G
M
H
L
P
K
S
V
S
S
S
P
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.4
82.3
N.A.
79.7
26
N.A.
55
59.2
51.6
50.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98
86.8
N.A.
84.8
41.2
N.A.
63.6
69
62.9
64.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
20
6.6
N.A.
20
0
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
20
20
N.A.
26.6
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
10
20
10
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
10
10
0
0
0
10
0
10
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
20
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% F
% Gly:
0
10
0
0
10
10
10
0
10
0
10
0
0
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
50
10
0
40
0
0
10
0
10
10
10
40
40
0
20
% K
% Leu:
0
40
10
20
10
50
10
0
10
0
0
20
0
10
0
% L
% Met:
0
0
20
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% N
% Pro:
10
0
40
0
0
10
10
10
0
40
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
10
0
0
0
10
10
0
20
0
0
0
0
10
% R
% Ser:
0
20
20
10
60
30
50
70
40
20
10
20
0
10
10
% S
% Thr:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
20
0
50
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _